…Hogg spoke to Peter Diamandis the co-founder of the Singularity University from California, which is a benefit corporation funding technological…
Wearable technology is the future. There’s just one problem. No one wants to wear the stuff. One potential solution? Make it invisible. Weave it into already existing products so seamlessly... read more
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Van Coller: How Salim Ismail s masterpiece opens up world of 10x and ExOs In Silicon Valley, 10x has become part of the vernacular. It translates…
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MIT researchers have found they were able to reactivate memories in mice that could not otherwise be retrieved, using optogenetics — in which proteins are added to neurons to allow them to be activated with light.
The breakthrough finding, in a paper published Thursday (May 28) in the journal Science, appears to answer a longstanding question in neuroscience regarding amnesia.
Damaged or blocked memory?
Neuroscience researchers have for many years debated whether retrograde amnesia — which follows traumatic injury, stress, or diseases such as Alzheimer’s — is caused by damage to specific brain cells, meaning a memory cannot be stored, or if access to that memory is somehow blocked, preventing its recall.
The answer, according to Susumu Tonegawa, the Picower Professor in MIT’s Department of Biology and director of the RIKEN-MIT Center at the Picower Institute for Learning and Memory: “Amnesia is a problem of retrieval impairment.”
Memory researchers have previously speculated that somewhere in the brain network is a population of neurons that are activated during the process of acquiring a memory, causing enduring physical or chemical changes.
If these groups of neurons are subsequently reactivated by a trigger such as a particular sight or smell, for example, the entire memory is recalled. These neurons are known as “memory engram cells.”
Blocking, then activating memories with light
Until now, no one has been able to show that these groups of neurons undergo enduring chemical changes, in a process known as memory consolidation. One such change, known as “long-term potentiation” (LTP), involves the strengthening of synapses, the structures that allow groups of neurons to send signals to each other, as a result of learning and experience.
To find out if these chemical changes do indeed take place, the researchers first identified a group of engram cells in the hippocampus that, when activated using optogenetic tools, were able to express a memory.
When they then recorded the activity of this particular group of cells, they found that the synapses connecting them had been strengthened. “We were able to demonstrate for the first time that these specific cells — a small group of cells in the hippocampus — had undergone this augmentation of synaptic strength,” Tonegawa says.
The researchers then attempted to discover what happens to memories without this consolidation process. By administering a compound called anisomycin, which blocks protein synthesis within neurons, immediately after mice had formed a new memory, the researchers were able to prevent the synapses from strengthening.
When they returned one day later and attempted to reactivate the memory using an emotional trigger, they could find no trace of it. “So even though the engram cells are there, without protein synthesis those cell synapses are not strengthened, and the memory is lost,” Tonegawa says.
But startlingly, when the researchers then reactivated the protein synthesis-blocked engram cells using optogenetic tools, they found that the mice exhibited all the signs of recalling the memory in full.
“If you test memory recall with natural recall triggers in an anisomycin-treated animal, it will be amnesiac, you cannot induce memory recall,” Tonegawa says. “But if you go directly to the putative engram-bearing cells and activate them with light, you can restore the memory, despite the fact that there has been no LTP.”
Memories are stored in a circuit of groups of cells in multiple brain areas, not synapses
Further studies carried out by Tonegawa’s group demonstrated that memories are stored not in synapses strengthened by protein synthesis in individual engram cells, but in a circuit, or “pathway” of multiple groups of engram cells and the connections between them.
“We are proposing a new concept, in which there is an engram cell ensemble pathway, or circuit, for each memory,” he says. “This circuit encompasses multiple brain areas and the engram cell ensembles in these areas are connected specifically for a particular memory.”
The research dissociates the mechanisms used in memory storage from those of memory retrieval, according to Ryan. “The strengthening of engram synapses is crucial for the brain’s ability to access or retrieve those specific memories, while the connectivity pathways between engram cells allows the encoding and storage of the memory information itself,” he says.
Changes in synaptic strength and in spine properties have long been associated with learning and memory, according to Alcino Silva, director of the Integrative Center for Learning and Memory at the University of California at Los Angeles.
“This groundbreaking paper suggests that these changes may not be as critical for memory as once thought, since under certain conditions, it seems to be possible to disrupt these changes and still preserve memory,” he says. “Instead, it appears that these changes may be needed for memory retrieval, a mysterious process that has so far evaded neuroscientists.”
Abstract of Engram cells retain memory under retrograde amnesia
Memory consolidation is the process by which a newly formed and unstable memory transforms into a stable long-term memory. It is unknown whether the process of memory consolidation occurs exclusively through the stabilization of memory engrams. By using learning-dependent cell labeling, we identified an increase of synaptic strength and dendritic spine density specifically in consolidated memory engram cells. Although these properties are lacking in engram cells under protein synthesis inhibitor–induced amnesia, direct optogenetic activation of these cells results in memory retrieval, and this correlates with retained engram cell–specific connectivity. We propose that a specific pattern of connectivity of engram cells may be crucial for memory information storage and that strengthened synapses in these cells critically contribute to the memory retrieval process.
Lightly stimulating the brain with transcranial direct current stimulation (tDCS) may improve short-term memory in people with schizophrenia, according to a new study by researchers at the Johns Hopkins University School of Medicine.
The tDCS procedure involves placing sponge-covered electrodes on the head and passing a weak electrical current between them.
David Schretlen, Ph.D., a professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine, reasoned that this type of brain stimulation might ease some of the cognitive difficulties that afflict people with schizophrenia.
A test based on prefrontal cortex stimulation
To test that possibility, Schretlen and Johns Hopkins colleagues targeted a brain region called the left dorsolateral prefrontal cortex, which plays an important role in short-term or working memory and is abnormal in people with schizophrenia, according to Schretlen.
Schretlen recruited 11 participants: five adults with confirmed schizophrenia and six of their close relatives (parents, siblings, and children of people with schizophrenia show some of the same abnormalities to a lesser degree, says Schretlen).
Each participant received two 30-minute treatments — one using a negative electrical charge, which the researchers thought might prove beneficial — and the other using a positive charge as a control. During and after each treatment, participants completed a battery of cognitive tests.
There were two notable results:
- On tests of verbal and visual working memory, participants performed significantly better after receiving a negative charge, and the effects were “surprisingly strong,” says Schretlen.
- Participants did better at the challenging task of switching between naming categories of items in a supermarket after a negatively charged treatment. The stimulation “was associated with better performance on working memory and subtle changes in word retrieval,” Schretlen says. People with schizophrenia often struggle to find the right words, he says. Because the prefrontal cortex contains a brain region responsible for word retrieval, Schretlen reasoned that transcranial direct current stimulation might help.
Schretlen is now studying transcranial direct current stimulation in a larger sample of patients using repeated sessions of stimulation, which he hopes will induce lasting benefits.
“Cognitive impairment is as ubiquitous as hallucinations in schizophrenia, yet medications only treat the hallucinations,” Schretlen says. “So even with medication, affected individuals often remain very disabled.” His hope is that transcranial direct current stimulation could give people with schizophrenia a shot at leading a more normal life.
A related study last year showed that tDCS improved correction of mistakes. But another recent study found that after a repeated IQ test (which is normally expected to show improvements), IQ scores of people who underwent tDCS brain stimulation improved markedly less than did the IQ scores of people in the placebo group.
The tDCS procedure is also being studied by other researchers as a treatment for depression and Alzheimer’s-related memory loss, and to enhance recovery following strokes.
The research is described in a paper published online in Clinical Schizophrenia and Related Psychoses. The study was funded by the Therapeutic Cognitive Neuroscience Professorship; the Therapeutic Cognitive Neuroscience Fund; the Benjamin and Adith Miller Family Endowment on Aging, Alzheimer’s and Autism; and the National Institute on Child and Human Development.
Abstract of Can Transcranial Direct Current Stimulation Improve Cognitive Functioning in Adults with Schizophrenia?
Cognitive impairment is nearly ubiquitous in schizophrenia. First-degree relatives of persons with schizophrenia often show similar but milder deficits. Current methods for the treatment of schizophrenia are often ineffective in cognitive remediation. Since transcranial direct current stimulation (tDCS) can enhance cognitive functioning in healthy adults, it might provide a viable option to enhance cognition in schizophrenia. We sought to explore whether tDCS can be tolerated by persons with schizophrenia and potentially improve their cognitive functioning. We examined the effects of anodal versus cathodal tDCS on working memory and other cognitive tasks in five outpatients with schizophrenia and six first-degree relatives of persons with schizophrenia. Each participant completed tasks thought to be mediated by the prefrontal cortex during two 30-minute sessions of tDCS to the left and right dorsolateral prefrontal cortex (DLPFC). Anodal stimulation over the left DLPFC improved performance relative to cathodal stimulation on measures of working memory and aspects of verbal fluency relevant to word retrieval. The patient group showed differential changes in novel design production without alteration of overall productivity, suggesting that tDCS might be capable of altering selfmonitoring and executive control. All participants tolerated tDCS well. None withdrew from the study or experienced any adverse reaction. We conclude that adults with schizophrenia can tolerate tDCS while engaging in cognitive tasks and that tDCS can alter their performance.
University of Wisconsin-Madison and U.S. Department of Agriculture Forest Products Laboratory (FPL) researchers have jointly developed a wood chip in an effort to alleviate the environmental burden* of electronic devices.
Well, actually, a wood-substrate-based semiconductor chip. They replaced the silicon substrate portion in a conventional chip with environment-friendly cellulose nanofibril (CNF). CNF is a flexible, biodegradable material made from wood, as the researchers note in an open-access paper published May 26 in the journal Nature Communications.
“[More than 99%] of the material in a chip is support,” said Zhiyong Cai, project leader of an engineering composite science research group at FPL. With the new substrate, the chips are “so safe you can put them in the forest and fungus will degrade it. They become as safe as fertilizer.”
The new material is especially important for microwave chips (such as those used in mobile phones) made with gallium arsenide, which is especially difficult to fabricate on foreign substrates. That’s because of the small feature sizes and high temperature processes required for high performance.
Cai’s group addressed two key barriers to using wood-derived materials in an electronics setting: surface roughness and thermal expansion. “You don’t want it to expand or shrink too much. Wood is a natural hydroscopic [water-absorbing] material and could attract moisture from the air and expand,” Cai says. “With an epoxy coating on the surface of the CNF, we solved both [problems].”
* In 2007, it was estimated that over 426,000 cell phones (most of them were still functional) and 112,000 computers were discarded every day in the US, totalling 3.2 million tons of electronic waste generated per year, the researcher note in the paper.
Abstract of High-performance green flexible electronics based on biodegradable cellulose nanofibril paper
Today’s consumer electronics, such as cell phones, tablets and other portable electronic devices, are typically made of non-renewable, non-biodegradable, and sometimes potentially toxic (for example, gallium arsenide) materials. These consumer electronics are frequently upgraded or discarded, leading to serious environmental contamination. Thus, electronic systems consisting of renewable and biodegradable materials and minimal amount of potentially toxic materials are desirable. Here we report high-performance flexible microwave and digital electronics that consume the smallest amount of potentially toxic materials on biobased, biodegradable and flexible cellulose nanofibril papers. Furthermore, we demonstrate gallium arsenide microwave devices, the consumer wireless workhorse, in a transferrable thin-film form. Successful fabrication of key electrical components on the flexible cellulose nanofibril paper with comparable performance to their rigid counterparts and clear demonstration of fungal biodegradation of the cellulose-nanofibril-based electronics suggest that it is feasible to fabricate high-performance flexible electronics using ecofriendly materials.
Video Friday: Dr. Max More at the Church of Perpetual Life — Cryonics & the Future of Emergency Medicine
A recording of yesterday’s live event at the Church of Perpetual Life including a presentation by Max More.
(There were some internet connectivity issues during the live streaming so there are also some bad spots in the replay. It is not a problem with your connection.)
Dr. Max More is a Strategic Philosopher, President & CEO of Alcor Life Extension Foundation, and author of the Proactionary Principle and the philosophy of Extropy and Transhumanism. An internationally recognized advocate of the effective and ethical use of technology for life extension and cryopreservation, Dr. Max More co-founded the Extropy Institute, an educational non-profit organization that created the modern “transhumanist” movement, whose goals centrally include extending healthy human life span.
Marvin Minsky, “the father of artificial intelligence”, said of Dr. More: “We have a dreadful shortage of people who know so much, can both think so boldly and clearly, and can express themselves so articulately.”
Live long and healthy!
Perpetual Life is a non-denominational science based church that is open to people of all faiths as well as the non-religious. We are non-judgmental and our members may belong to other churches. We hold faith in the technologies and discoveries of humanity to end aging and to defeat death within our lifetime.
Learn more at www.Perpetual.Life
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I open my eyes to a gritty, urban skyline dotted with airships. Looking down, I find my feet, the rooftop’s edge, and a vertiginous drop to the street below. Seconds... read more
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the bigger the challenge the greater the incentive needs to be. Peter Diamandis, co-founder of Singularity University, drew on the experience…
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Psychedelic drugs such as LSD are much less harmful than claimed and should be legally reclassified to allow further research on their medical use, says James Rucker, a psychiatrist and honorary lecturer at the Institute of Psychiatry, Psychology and Neuroscience, King’s College London.
These substances “were extensively used and researched in clinical psychiatry” before their prohibition in 1967 and many trials of these drugs in the 1950s and 1960s suggested “beneficial change in many psychiatric disorders.”
Nonetheless, in the UK, psychedelic drugs were legally classified as schedule 1 class A drugs; that is, as having “no accepted medical use and the greatest potential for harm, despite the research evidence to the contrary,” he writes.
Clinical efficacy shown in anxiety, obsessive compulsive disorder, addiction, and headaches
Rucker makes these points:
- Psychedelics remain more legally restricted than heroin and cocaine. “But no evidence indicates that psychedelic drugs are habit forming; little evidence indicates that they are harmful in controlled settings; and much historical evidence shows that they could have use in common psychiatric disorders.” In fact, recent studies indicate that psychedelics have “clinical efficacy in anxiety associated with advanced cancer, obsessive compulsive disorder, tobacco and alcohol addiction, and cluster headaches,” he writes.
- At present, larger clinical studies on psychedelics are made “almost impossible by the practical, financial and bureaucratic obstacles” imposed by their schedule 1 classification. Currently, only one manufacturer in the world produces psilocybin for trial purposes, he says, at a “prohibitive” cost of £100,000 for 1 g (50 doses).
- In the UK, to hold a schedule 1 drug, institutions require a license, which costs about £5,000, he adds. Only four hospitals currently hold such licenses, which come with regular police or home office inspections and onerous rules on storage and transport, so “clinical research using psychedelics costs 5–10 times that of research into less restricted (but more harmful) drugs such as heroin.” As a result, “almost all grant funders are uncomfortable funding research into psychedelics,” while prohibition as a condition of UN membership is “arguably causing more harm than it prevents.”
- Psychedelics are neither harmful nor addictive compared with other controlled substances. He calls on the UK Advisory Council on the Misuse of Drugs and the 2016 UN General Assembly Special Session on Drugs, “to recommend that psychedelics be reclassified as schedule 2 compounds to enable a comprehensive, evidence based assessment of their therapeutic potential.”
The Beatles — A Day in the Life
University of Houston researchers have developed a concept for MRI-powered millimeter-size “millirobots” that could one day perform unprecedented minimally invasive medical treatments.
This technology could be used to treat hydrocephalus, for example. Current treatments require drilling through the skull to implant pressure-relieving shunts, said Aaron T. Becker, assistant professor of electrical and computer engineering at the University of Houston.
But MRI scanners alone don’t produce enough force to pierce tissues (or insert needles). So the researchers drew upon the principle of the “Gauss gun.”
K&J Magnetics | Gauss Gun Demonstrations
Here’s how the a Gauss gun works: a single steel ball rolls down a chamber, setting off a chain reaction when it smashes into the next ball, etc., until the last ball flies forward, moving much more quickly the initial ball.
Based on that concept, the researchers imagine a medical robot with a barrel self-assembled from three small high-impact 3D-printed plastic components, with slender titanium rod spacers separating two steel balls.
Aaron T. Becker, assistant professor of electrical and computer engineering at the University of Houston, said the potential technology could be used to treat hydrocephalus and other conditions, allowing surgeons to avoid current treatments that require cutting through the skull to implant pressure-relieving shunts.
Becker was first author of a paper presented at ICRA, the conference of the IEEE Robotics and Automation Society, nominated for best conference paper and best medical robotics paper.
“Hydrocephalus, among other conditions, is a candidate for correction by our millirobots because the ventricles are fluid-filled and connect to the spinal canal,” Becker said. “Our noninvasive approach would eventually require simply a hypodermic needle or lumbar puncture to introduce the components into the spinal canal, and the components could be steered out of the body afterwards.”
Future work will focus on exploring clinical context, miniaturizing the device, and optimizing material selection.
Abstract of Toward Tissue Penetration by MRI-powered Millirobots Using a Self-Assembled Gauss Gun
MRI-based navigation and propulsion of millirobots is a new and promising approach for minimally invasive therapies. The strong central field inside the scanner, however, precludes torque-based control. Consequently, prior propulsion techniques have been limited to gradient-based pulling through fluid-filled body lumens. This paper introduces a technique for generating large impulsive forces that can be used to penetrate tissue. The approach is based on navigating multiple robots to a desired location and using self-assembly to trigger the conversion of magnetic potential energy into sufficient kinetic energy to achieve penetration. The approach is illustrated through analytical modeling and experiments in a clinical MRI scanner.
According to a senior fellow for Lockheed IT, the National Security Agency has tested the use of smartphone-swipe recognition technology dubbed Mandrake.
The NSA has developed a new technology, dubbed “Mandrake“, that can identify users from the way they swipe strokes and text on a smartphone screen. The news was reported by officials withLockheed Martin who helped design the technology.
According to John Mears, a senior fellow for Lockheed IT and Security Solutions, that Lockheed Martin has recently tested swipe recognition technology that allow the identification of smartphone users based on how they type on their mobile devices.
“The National Security Agency has tested the use of smartphone-swipe recognition technology, according to the tool’s manufacturer. The mobile device feature, created by Lockheed Martin, verifies a user’s identity based on the swiftness and shape of the individual’s finger strokes on a touch screen.” reported by Nextgov.
Mandrake is able to remotely analyze the curve, unique speed and acceleration of a person’s finger stroke across the touch screen of their smartphone, this information are unique for each individual as explained Mears.
“Nobody else has the same strokes,” explained Mears. “People can forge your handwriting in two dimensions, but they couldn’t forge it in three or four dimensions.” “Three is the pressure you put in, also to the two dimensions on the paper. The fourth dimension is time. The most advanced handwriting-type authentication tracks you in four dimensions.“Officially, the NSA has developed the Mandrake technology for authentication purpose and it is already available to the Agency, but privacy advocates fear a possible use for surveillance activities.
“We’ve done work with the NSA with that for secure gesture authentication as a technique for using smartphones,” Mears said. “They are actually able to use it.”John Mears added that the Mandrake technology could be used for emergency responders who do not have the capability to access an incident command website.“If you are going 100 miles down the road, you are not going to enter a complex 12-character password to authenticate yourself,” he said. “We have some customers who deal with radioactive material and they can’t touch things” that small with gloves on — “How do they authenticate?”
Nextgov reported that Lockheed Martin was involved in other projects with the US Government that could represent a serious threat for people’s privacy, the news agency referred a project committed by the FBI for a $1 billion facial, fingerprint, palm print, retina scan and tattoo image biometric ID system. The FBI’s project, dubbed the Next Generation Identification system, could allow in a short future to identify a person from its voice and on how it walks.
###Pierluigi Paganini is Chief Information Security Officer at Bit4Id, firm leader in identity management, member of the ENISA (European Union Agency for Network and Information Security)Treat Landscape Stakeholder Group, he is also a Security Evangelist, Security Analyst and Freelance Writer. Editor-in-Chief at “Cyber Defense Magazine”, Pierluigi is a cyber security expert with over 20 years experience in the field, he is Certified Ethical Hacker at EC Council in London. The passion for writing and a strong belief that security is founded on sharing and awareness led Pierluigi to find the security blog “Security Affairs” recently named a Top National Security Resource for US. Pierluigi is a member of the “The Hacker News” team and he is a writer for some major publications in the field such as Cyber War Zone, ICTTF, Infosec Island, Infosec Institute, The Hacker News Magazine and for many other Security magazines. Author of the Books “The Deep Dark Web” and “Digital Virtual Currency and Bitcoin”.
[Editor’s note: see also http://www.connectidexpo.com/creo_files/expo2014-slides/connectID%20slides.pdf where the idea of using “swipe behavior” is previously reported.]
If you’ve ever watched a child trying to fit a shape into a cut-out, you might get a flash of déjà vu in the following robot video. It takes some... read more
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Heat shock proteins such as HSP70 are molecular chaperones involved in cellular housekeeping processes that clear out damaged or misfolded proteins. Their activity increases in response to heat, toxins, and various other forms of cellular stress, and dialing up the activity of heat shock proteins is involved in a number of methods demonstrated to slow aging in laboratory animals. There are a few programs underway in the research community aimed at producing therapies that increase heat shock protein activity, especially for neurodegenerative conditions involving protein aggregates, but nothing that has yet made the leap into later stages of development and higher levels of funding:Reducing the levels of toxic protein aggregates has become a focus of therapy for disorders like Alzheimer's and Parkinson's diseases, as well as for the general deterioration of cells and tissues during aging. One approach has been an attempt to influence the production or activity of a class of reparative chaperones called heat shock proteins (HSPs), of which HSP70 is a promising candidate. Manipulation of HSP70 expression results in disposal of misfolded protein aggregates that accumulate in aging and disease models. Recently, HSP70 has been shown to bind specifically to an amino-terminal sequence of a human diffusible survival evasion peptide (DSEP), dermcidin. This sequence includes CHEC-9, an orally available anti-inflammatory and cell survival peptide.
In the present study, we found that the CHEC-9 peptide also binds HSP70 in the cytosol of the cerebral cortex after oral delivery in normal rats. Western analysis suggested that peptide treatment increased the level of active HSP70 monomers from the pool of chaperone oligomers, a process that may be stimulated by potentiation of the chaperone's adenosine triphosphatase (ATPase). In these samples, a small but consistent gel shift was observed for glyceraldehyde 3-phosphate dehydrogenase (GAPDH), a multifunctional protein whose aggregation is influenced by HSP70. CHEC-9 treatment of an in vitro model of α-synuclein aggregation also results in HSP70-dependent dissolution of these aggregates.
HSP70 oligomer-monomer equilibrium and its potential to control protein aggregate disease warrant increased experimental attention, especially if a peptide fragment of an endogenous human protein can influence the process.
In recent years, researchers have provided evidence to suggest that cellular senescence mechanisms are partly involved in the decline of stem cell activity in aging. It is an open question as to how this interacts with other signaling mechanisms also recently shown to influence the suppression of stem cell tissue maintenance. This is one part of a larger discussion over the degree to which loss of stem cell activity is due to internal factors localized within the stem cell populations, such as cellular damage, or external factors such as changes in cell signaling systems that are a reaction to more widespread damage in tissues:Regeneration of skeletal muscle relies on a population of quiescent stem cells (satellite cells) and is impaired in very old (geriatric) individuals undergoing sarcopenia. Stem cell function is essential for organismal homeostasis, providing a renewable source of cells to repair damaged tissues. In adult organisms, age-dependent loss-of-function of tissue-specific stem cells is causally related with a decline in regenerative potential. Although environmental manipulations have shown good promise in the reversal of these conditions, recently we demonstrated that muscle stem cell aging is, in fact, a progressive process that results in persistent and irreversible changes in stem cell intrinsic properties.
Global gene expression analyses uncovered an induction of p16INK4a in satellite cells of physiologically aged geriatric and progeric mice that inhibits satellite cell-dependent muscle regeneration. Aged satellite cells lose the repression of the INK4a locus, which switches stem cell reversible quiescence into a pre-senescent state; upon regenerative or proliferative pressure, these cells undergo accelerated senescence (geroconversion), through Rb-mediated repression of E2F target genes. p16INK4a silencing rejuvenated satellite cells, restoring regeneration in geriatric and progeric muscles. Thus, p16INK4a/Rb-driven stem cell senescence is causally implicated in the intrinsic defective regeneration of sarcopenic muscle. Here we discuss on how cellular senescence may be a common mechanism of stem cell aging at the organism level and show that induction of p16INK4a in young muscle stem cells through deletion of the Polycomb complex protein Bmi1 recapitulates the geriatric phenotype.
Engineers at The Ohio State University claim they have created a circuit that makes cell phone batteries last up to 30 percent longer on a single charge. The trick: it converts some of the radio signals emanating from a phone into direct current (DC) power, which then charges the phone’s battery, they state.
This new technology can be built into a cell phone case, adding minimal bulk and weight.
“When we communicate with a cell tower or Wi-Fi router, so much energy goes to waste,” explained Chi-Chih Chen, research associate professor of electrical and computer engineering. “We recycle some of that wasted energy back into the battery.”
“Our technology is based on harvesting energy directly from the source, explained Robert Lee, professor of electrical and computer engineering. By Lee’s reckoning, nearly 97 percent of cell phone signals never reach a destination and are simply lost. Some of the that energy can be captured.
The idea is to siphon off just enough of the radio signal to noticeably slow battery drain, but not enough to degrade voice quality or data transmission. Cell phones broadcast in all directions at once to reach the nearest cell tower or Wi-Fi router. Chen and his colleagues came up with a system that identifies which radio signals are being wasted. It works only when a phone is transmitting.
Next, the engineers want to insert the device into a “skin” that sticks directly to a phone, or better, partner with a manufacturer to build it directly into a phone, tablet or other portable electronic device.
UPDATE June 6: Responding to a request for more information on energy harvesting, we received the following statement from Will Zell, CEO of licensee Nikola Labs: “Nikola Labs has a limit to the technical details we are able to share until our patents are published.”
Disney researchers have found a way for a robot to mimic an animated character’s walk, bringing a cartoon (or other) character to life in the real world.
Beginning with an animation of a diminutive, peanut-shaped character that walks with a rolling, somewhat bow-legged gait, Katsu Yamane and his team at Disney Research Pittsburgh analyzed the character’s motion to design a robotic frame that could duplicate the walking motion. using 3D-printed links and servo motors, while also fitting inside the character’s skin. They then created control software that could keep the robot balanced while duplicating the character’s gait as closely as possible.
“The biggest challenge is that designers don’t necessarily consider physics when they create an animated character,” said Yamane, senior research scientist. Roboticists, however, wrestle with physical constraints throughout the process of creating a real-life version of the character.
“It’s important that, despite physical limitations, we do not sacrifice style or the quality of motion,” Yamane said. The robots will need to not only look like the characters, but move in the way people are accustomed to seeing those characters move.
The researchers are describing the techniques and technologies they used to create the bipedal robot at the IEEE International Conference on Robotics and Automation, ICRA 2015, May 26–30 in Seattle.
DisneyResearchHub | Development of a Bipedal Robot that Walks Like an Animation Character
What if your handheld tools knew what needs to be done and were even able to guide and help you complete jobs that require skills? University of Bristol researchers are finding out by building and testing intelligent handheld robots.
Think of them as smart power tools that “know” what they’re doing — and could even help you use them.
The robot tools would have three levels of autonomy, said Walterio Mayol-Cuevas, Reader in Robotics Computer Vision and Mobile Systems: “No autonomy, semi-autonomous — the robot advises the user but does not act, and fully autonomous — the robot advises and acts even by correcting or refusing to perform incorrect user actions.”
The Bristol team has experimented with tasks such as picking and dropping different objects to form tile patterns and aiming in 3D for simulated painting.
The robot designs are open source and available on the university’s HandheldRobotics page.
HandheldRobotics | The Design and Evaluation of a Cooperative Handheld Robot
A tiny (one-centimeter-square) biosensor chip developed at EPFL is designed to be implanted under your skin to continuously monitor concentrations of pH, temperature, and metabolism-related molecules like glucose, lactate and cholesterol, as well as some drugs.
The chip would replace blood work, which may take hours — or even days — for analysis and is a limited snapshot of conditions at the moment the blood is drawn.
Developer Sandro Carrara unveiled the chip Tuesday (May 26) at the International Symposium on Circuits and Systems (ISCAS) in Lisbon.
The electrochemical sensors work with or without enzymes, which means the device can react to a wide range of compounds, and it can do so for several days or even weeks.
Wireless power and monitoring
The biochip contains three main components: a circuit with six sensors, a control unit that analyzes incoming signals, and a Bluetooth module for sending the results immediately to a mobile phone.
It also has an induction coil that wirelessly draws power from an external battery attached to the skin by a patch.
To ensure biocompatibility, an epoxy-enhanced polyurethane membrane was used to cover the device.
The chip was successfully tested in vivo on mice at the Institute for Research in Biomedicine (IRB) in Bellinzona, where researchers were able to constantly monitor glucose and paracetamol levels without a wire tracker getting in the way of the animals’ daily activities.
The results were promising, so clinical tests on humans could take place in three to five years — especially since the procedure is minimally invasive, the researchers say.
“Knowing the precise and real-time effect of drugs on the metabolism is one of the keys to the type of personalised, precision medicine that we are striving for,” said Carrara.